Title : A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

Pub. Date : 2002 Mar 15

PMID : 11889037






1 Functional Relationships(s)
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1 While it is known that the DH domain is the principal catalytic subunit, recent biochemical data indicate that for some Dbl-family proteins, such as Dbs and Trio, PH domains may cooperate with their associated DH domains in promoting guanine nucleotide exchange of Rho GTPases. Guanine Nucleotides MCF.2 cell line derived transforming sequence Homo sapiens