Pub. Date : 2002 Apr
PMID : 11888570
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The 5-HT(1A) receptors in the DRN play a role in mediating the anxiolytic effects of nicotine and the 5-HT(1A) receptors in the dorsal hippocampus and lateral septum mediate its anxiogenic effects. | Nicotine | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 2 | The increased startle and anxiety during nicotine withdrawal is mediated by 5-HT(1A) and 5-HT(3) receptors. | Nicotine | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 3 | The locomotor stimulant effect of acute nicotine is mediated by 5-HT(1A) receptors and 5-HT(2) receptors may play a role in the expression of a sensitised response after chronic nicotine treatment. | Nicotine | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 4 | Unfortunately, the role of 5-HT(1A) receptors in mediating nicotine seeking has not yet been investigated and would seem an important area for future research. | Nicotine | 5-hydroxytryptamine receptor 1A | Homo sapiens |