Title : Irregular spiking in free calcium concentration in single, human platelets. Regulation by modulation of the inositol trisphosphate receptors.

Pub. Date : 2002 Mar

PMID : 11874470






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Fluorescence ratio imaging indicates that immobilized, aspirin-treated platelets, loaded with Fura-2, respond to inositol 1,4,5-trisphosphate- (InsP3)-generating agonists such as thrombin by high-frequency, irregular rises in cytosolic [Ca2+]i with spikes that vary in peak level and peak-to-peak interval. Fura-2 coagulation factor II, thrombin Homo sapiens