Title : NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.

Pub. Date : 2002 Mar

PMID : 11872668






1 Functional Relationships(s)
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1 Significantly, the actions of both GLP-1 and forskolin were abolished by the selective Ca(2+)/calmodulin-dependent phosphatase 2B (calcineurin) inhibitor, FK506, as well as by the chelation of intracellular Ca(2+) by BAPTA (bis(2-aminophenoxy)ethane-N,N,N",N"-tetraacetate). Tacrolimus glucagon Rattus norvegicus