Title : [Effects of hypoxia on the expression of protein kinase C mRNA in pulmonary artery smooth muscle and endothelial cell].

Pub. Date : 2001 Jun

PMID : 11866979






4 Functional Relationships(s)
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Protein Name
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1 The expression of PKC alpha mRNA was higher in the PASMC of intra-acinar pulmonary arteriole than that of muscular arteriole (P < 0.01). pasmc protein kinase C, alpha Rattus norvegicus
2 PKC alpha mRNA was expressed in normal PASMC and EC in pigs in vitro. pasmc protein kinase C, alpha Rattus norvegicus
3 After 1 h of hypoxia, no change was detected, but PKC alpha mRNA expression was significantly higher after 48 h and 72 h of hypoxia in PASMC and EC in vitro (P < 0.01). pasmc protein kinase C, alpha Rattus norvegicus
4 CONCLUSIONS: Hypoxia can promote expression of PKC alpha m RNA in PASMC and EC, especially in the PASMC of intra-acinar pulmonary arterioles. pasmc protein kinase C, alpha Rattus norvegicus