Title : The Effect of Misoprostol on Arachidonic Acid Mobilization, Prostaglandin E(2), Production, and IL-1beta Signaling.

Pub. Date : 1995 Sep

PMID : 11854839






2 Functional Relationships(s)
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1 We found that both IL-1beta and misoprostol induced arachidonic acid release, suggesting enhanced phospholipase A(2) activation. Arachidonic Acid interleukin 1 beta Homo sapiens
2 Together, the results suggest that misoprostol may upregulate the conversion of arachidonic acid to PGE(2) by enhancing the IL-1beta-induced activation/synthesis of cyclooxygenase. Arachidonic Acid interleukin 1 beta Homo sapiens