Title : Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs.

Pub. Date : 2002 Feb 19

PMID : 11842200






1 Functional Relationships(s)
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Protein Name
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1 An AU rich element (ARE) in the 3" noncoding region promotes the rapid degradation of mammalian cytokine and proto-oncogene mRNAs, such as tumor necrosis factor-alpha, granulocyte-macrophage colony-stimulating factor (GM-CSF) and c-fos. Gold Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens