Title : Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Pub. Date : 2002 Jan

PMID : 11841938






1 Functional Relationships(s)
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1 We used olefin metathesis to synthesize C40 derivatives of FK506 and measured their ability, when complexed to FKBP12, to inhibit calcineurin"s phosphatase activity. Tacrolimus FKBP prolyl isomerase 1A pseudogene 4 Homo sapiens