Title : p53-mediated downregulation of Chk1 abrogates the DNA damage-induced G2M checkpoint in K562 cells, resulting in increased apoptosis.

Pub. Date : 2002 Feb

PMID : 11841447






1 Functional Relationships(s)
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1 p53-transfected and control cells were treated with etoposide and trapped at mitosis with nocodazole. Nocodazole tumor protein p53 Homo sapiens