Title : IL-12 or IL-15, unlike IL-2, does not interact with histamine in augmenting cytotoxicity of splenocytes against melanoma cells and YAC-1 cells.

Pub. Date : 2002 Mar-Apr

PMID : 11836621






2 Functional Relationships(s)
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1 Histamine thus reverses negative regulation of NK cells treated with IL-2 and IFN-alpha in the presence of macrophages. Histamine interleukin 2 Mus musculus
2 We confirm that histamine potently enhances cytotoxic activity of IL-2-stimulated NK cell-enriched splenocytes admixed with macrophages against B16F10 melanoma cells and YAC-1 cells. Histamine interleukin 2 Mus musculus