Title : Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner.

Pub. Date : 2002 Feb

PMID : 11835680






2 Functional Relationships(s)
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1 Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner. Caffeine tumor protein p53 Homo sapiens
2 Surprisingly, at a concentration of 5 mM, caffeine not only induced apoptosis by itself and acted synergistically to enhance radiation-induced apoptosis, but also induced a TP53-independent G(1)-phase arrest. Caffeine tumor protein p53 Homo sapiens