Pub. Date : 1975 Oct
PMID : 1182938
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Experiments were undertaken to investigate further the effect of furosemide on renin secretion in the anesthetized dog. | Furosemide | renin | Canis lupus familiaris |
2 | Furosemide, in a dose of 5 mg/kg, increased renin secretion and decreased renal resistance in dogs with a nonfiltering kidney. | Furosemide | renin | Canis lupus familiaris |
3 | However, following dilation of the intact filtering kidney with acetylcholine, furosemide caused an increase in renin secretion. | Furosemide | renin | Canis lupus familiaris |
4 | Following propranolol treatment, furosemide increased renin secretion in the filtering kidney but had no effect on renal resistance. | Furosemide | renin | Canis lupus familiaris |
5 | These experiments indicate that furosemide stimulates renin secretion by both the macula densa and the baroreceptor mechanisms. | Furosemide | renin | Canis lupus familiaris |