Pub. Date : 2001
PMID : 11820612
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Proline analogue of melphalan as a prolidase-convertible pro-drug in breast cancer MCF-7 cells. | Proline | peptidase D | Homo sapiens |
| 2 | Prolidase [E.C.3.4.13.9] is ubiquitously distributed cytosolic egzopeptidase that is known to cleave imido-bond of some low molecular weight compounds coupled to L-proline. | Proline | peptidase D | Homo sapiens |
| 3 | Previously we have found that conjugation of antineoplastic drug--melphalan (Mel) with proline (pro) through imido-bond resulted in formation of a good substrate for purified prolidase. | Proline | peptidase D | Homo sapiens |
| 4 | Previously we have found that conjugation of antineoplastic drug--melphalan (Mel) with proline (pro) through imido-bond resulted in formation of a good substrate for purified prolidase. | Proline | peptidase D | Homo sapiens |
| 5 | Cytosolic location of prolidase in neoplastic cells suggests that proline analogue of melphalan (Mel-pro) may serve as a prolidase convertable pro-drug. | Proline | peptidase D | Homo sapiens |
| 6 | Cytosolic location of prolidase in neoplastic cells suggests that proline analogue of melphalan (Mel-pro) may serve as a prolidase convertable pro-drug. | Proline | peptidase D | Homo sapiens |