Pub. Date : 1998 Feb
PMID : 11819223
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AIM:To study the p53 gene mutation and its relationship to aflatoxin B1 exposure in hepatocellular carcinoma (HCC).METHODS: Restriction fragment length polymorphism analysis method was used in 62 HCC samples, and DNA direct sequencing in another 45 HCC samples.RESULTS: In HCC and AFB1 high and low-risk areas, 36/52 (69%) and 2/10 (20%) cases were found losing the HaeIII allele respectively, suggesting one of the base G mutation at the p53 gene codon 249. | Aflatoxin B1 | tumor protein p53 | Homo sapiens |