Pub. Date : 2002
PMID : 11817979
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UNLABELLED: Quinapril is rapidly de-esterified after absorption to quinaprilat (the active diacid metabolite), a potent angiotensin converting enzyme (ACE) inhibitor. | Quinapril | angiotensin I converting enzyme | Homo sapiens |
| 2 | UNLABELLED: Quinapril is rapidly de-esterified after absorption to quinaprilat (the active diacid metabolite), a potent angiotensin converting enzyme (ACE) inhibitor. | Quinapril | angiotensin I converting enzyme | Homo sapiens |
| 3 | Quinapril produces favourable haemodynamic changes, and improves ventricular and endothelial function in patients with various cardiovascular disorders; these effects are mediated through the binding of quinaprilat to both tissue and plasma ACE. | Quinapril | angiotensin I converting enzyme | Homo sapiens |
| 4 | The tolerability of quinapril is similar to that of other ACE inhibitors. | Quinapril | angiotensin I converting enzyme | Homo sapiens |
| 5 | CONCLUSION: Quinapril is now firmly established as an effective and well tolerated ACE inhibitor for the treatment of patients with hypertension and congestive heart failure. | Quinapril | angiotensin I converting enzyme | Homo sapiens |