Title : Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules.

Pub. Date : 2002 Jan

PMID : 11809833






2 Functional Relationships(s)
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Protein Name
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1 Cells expressing a phosphomimetic mutant (S51D) of eIF2alpha assemble SGs of similar composition, confirming that the recruitment of these factors is a direct consequence of blocked translational initiation and not due to other effects of arsenite. arsenite eukaryotic translation initiation factor 2A Homo sapiens
2 Surprisingly, phospho-eIF2alpha is recruited to SGs that are disassembling in cells recovering from arsenite-induced stress. arsenite eukaryotic translation initiation factor 2A Homo sapiens