Pub. Date : 2002 Jan
PMID : 11807623
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The antimetastatic effect of a single low dose of cyclophosphamide involves modulation of galectin-1 and Bcl-2 expression. | Cyclophosphamide | galectin 1 | Rattus norvegicus |
| 2 | Since galectin-1 is expressed by highly metastatic tumors, in the present study we investigated the participation of this beta-galactoside-binding protein in cyclophosphamide-induced immunomodulation. | Cyclophosphamide | galectin 1 | Rattus norvegicus |
| 3 | Expression of galectin-1 was significantly decreased in tumors from cyclophosphamide-treated rats compared to non-treated rats. | Cyclophosphamide | galectin 1 | Rattus norvegicus |
| 4 | Our results suggest that a single low dose of cyclophosphamide modulates the expression of galectin-1 and Bcl-2 by tumors, which could in turn influence the apoptotic threshold of spleen mononuclear cells. | Cyclophosphamide | galectin 1 | Rattus norvegicus |