Title : TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells.

Pub. Date : 2002 Jan 10

PMID : 11803469






1 Functional Relationships(s)
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1 We demonstrate that in H157 human lung carcinoma cells, etoposide and doxorubicin induce the NF-kappaB-dependent expression of both pro- and anti-apoptotic proteins including TRAIL and its death receptor, DR5, and IAPs. Etoposide nuclear factor kappa B subunit 1 Homo sapiens