Title : Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes.

Pub. Date : 2002 Jan 11

PMID : 11792320






2 Functional Relationships(s)
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1 Dentatorubral-pallidoluysian atrophy is a progressive neurodegenerative disease caused by the expansion of a polyglutamine repeats within the Atrophin-1 protein. polyglutamine Grunge Drosophila melanogaster
2 Furthermore, both human Atrophin-1 and Drosophila Atrophin repress transcription in vivo when tethered to DNA, and poly-Q expansion in Atrophin-1 reduces this repressive activity. polyglutamine Grunge Drosophila melanogaster