Pub. Date : 2002 Jan
PMID : 11791142
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DESIGN: In vitro study of basal and insulin-stimulated 2-deoxyglucose uptake in human omental and subcutaneous adipose tissue explants derived from patients undergoing elective abdominal surgery. | Deoxyglucose | insulin | Homo sapiens |
| 2 | MEASUREMENTS: Fatness and fat distribution parameters (by anthropometry), basal and insulin stimulated [(3)H]-2-deoxyglucose uptake in omental and subcutaneous adipose tissue explants. | Deoxyglucose | insulin | Homo sapiens |
| 3 | RESULTS: In adipose tissue from lean subjects transport of 2-deoxyglucose over basal was stimulated approximately two-fold by insulin. | Deoxyglucose | insulin | Homo sapiens |
| 4 | Following incubation with 100-nM insulin for 35 min, insulin-stimulated 2-deoxyglucose transport was significantly lower in both omental and subcutaneous adipose tissue of obese and overweight compared to lean subjects. | Deoxyglucose | insulin | Homo sapiens |
| 5 | Following incubation with 100-nM insulin for 35 min, insulin-stimulated 2-deoxyglucose transport was significantly lower in both omental and subcutaneous adipose tissue of obese and overweight compared to lean subjects. | Deoxyglucose | insulin | Homo sapiens |
| 6 | The reduction in insulin-stimulated 2-deoxyglucose uptake seen in overweight and obese subjects was relatively similar in both depots. | Deoxyglucose | insulin | Homo sapiens |
| 7 | However, insulin responsive 2-deoxyglucose transport was significantly lower in the omental adipose tissue of subjects with central obesity, as compared to that of subjects with peripheral obesity. | Deoxyglucose | insulin | Homo sapiens |