Title : Role of IGF-I and IGF-binding proteins within diaphragm muscle in modulating the effects of nandrolone.

Pub. Date : 2002 Feb

PMID : 11788382






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Role of IGF-I and IGF-binding proteins within diaphragm muscle in modulating the effects of nandrolone. Nandrolone insulin-like growth factor 1 Rattus norvegicus
2 Role of IGF-I and IGF-binding proteins within diaphragm muscle in modulating the effects of nandrolone. Nandrolone insulin-like growth factor 1 Rattus norvegicus
3 The aim of this study was to examine the effects of nandrolone (NAN) on both IGF-I and IGF-binding proteins (IGFBPs) in the diaphragm muscle of 1-yr-old female rats. Nandrolone insulin-like growth factor 1 Rattus norvegicus
4 The aim of this study was to examine the effects of nandrolone (NAN) on both IGF-I and IGF-binding proteins (IGFBPs) in the diaphragm muscle of 1-yr-old female rats. Nandrolone insulin-like growth factor 1 Rattus norvegicus
5 The aim of this study was to examine the effects of nandrolone (NAN) on both IGF-I and IGF-binding proteins (IGFBPs) in the diaphragm muscle of 1-yr-old female rats. Nandrolone insulin-like growth factor 1 Rattus norvegicus
6 The aim of this study was to examine the effects of nandrolone (NAN) on both IGF-I and IGF-binding proteins (IGFBPs) in the diaphragm muscle of 1-yr-old female rats. Nandrolone insulin-like growth factor 1 Rattus norvegicus
7 Levels of IGF-I in the diaphragm muscle were significantly higher (50%) in NAN-treated animals. Nandrolone insulin-like growth factor 1 Rattus norvegicus
8 We conclude that NAN-induced diaphragm muscle fiber hypertrophy is mediated, in part, by influences of the IGF system within the muscle, such that coordinated changes in IGFBPs reflect a direction of change that has been associated with an anabolic response in other test systems. Nandrolone insulin-like growth factor 1 Rattus norvegicus