Title : Activated intrarenal transcription of CTL-effectors and TGF-beta1 in children with focal segmental glomerulosclerosis.

Pub. Date : 2002 Jan

PMID : 11786088






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 TGF-beta1 gene expression was noted in 23 of 29 steroid resistant (SR) children with NS not caused by lupus nephritis and in 18 of 20 FSGS patients. Steroids transforming growth factor beta 1 Homo sapiens
2 In contrast TGF-beta1 gene expression was detected in only 3 of 14 steroid-sensitive patients (P < 0.001). Steroids transforming growth factor beta 1 Homo sapiens
3 In patients with steroid-resistant NS, intrarenal TGF-beta1 gene expression showed a positive predictive value of 90% and a negative predictive value of 88% to identify FSGS (P < 0.0001). Steroids transforming growth factor beta 1 Homo sapiens