Title : Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis.

Pub. Date : 2002 Feb

PMID : 11784854






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LIM kinase 1 (LIMK1) phosphorylates cofilin, an actin-depolymerizing and -severing protein, at Ser-3 and regulates actin reorganization. Serine cofilin 1 Homo sapiens
2 We used a cell-permeable peptide (S3 peptide) that contains the phosphorylation site (Ser-3) of cofilin to inhibit the cellular function of LIMK1. Serine cofilin 1 Homo sapiens