Pub. Date : 2002 Jan 17
PMID : 11784143
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have taken a rational approach to designing inhibitors of P-glycoprotein function, selecting a natural substrate (progesterone) as our lead compound. | Progesterone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Potency for restoring doxorubicin accumulation in MDR1-transduced human breast cancer cells is increased up to 60-fold as compared with progesterone. | Progesterone | ATP binding cassette subfamily B member 1 | Homo sapiens |