Pub. Date : 2002 Mar 15
PMID : 11782484
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Plasmin reduction by phosphoglycerate kinase is a thiol-independent process. | Sulfhydryl Compounds | plasminogen | Homo sapiens |
| 2 | Alkylation/oxidation of Cys-379 and -380 by four different thiol-reactive compounds reduced plasmin reductase activity to 7--35% of control. | Sulfhydryl Compounds | plasminogen | Homo sapiens |
| 3 | In summary, reduction of plasmin by PGK is a thiol-independent process, although either alkylation/oxidation of the fast-reacting Cys near the hinge or hinge bending conformational change in PGK perturbs plasmin reduction by PGK, perhaps by obstructing the interaction of plasmin with PGK or perturbing conformational changes in PGK required for plasmin reduction. | Sulfhydryl Compounds | plasminogen | Homo sapiens |