Title : IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators.

Pub. Date : 2002 Jan 15

PMID : 11777983






2 Functional Relationships(s)
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1 EMSAs demonstrated that IL-17, IL-1beta, and TNF-alpha induced NF-kappaB activation within 1.5 h after stimulation, and a blockade of NF-kappaB activation by the pyrrolidine derivative of dithiocarbamate and tosyl-phe-chloromethylketone markedly reduced the IL-17-, IL-1beta-, or TNF-alpha-induced IL-6 gene expression. Dithiocarbamate interleukin 1 beta Homo sapiens
2 EMSAs demonstrated that IL-17, IL-1beta, and TNF-alpha induced NF-kappaB activation within 1.5 h after stimulation, and a blockade of NF-kappaB activation by the pyrrolidine derivative of dithiocarbamate and tosyl-phe-chloromethylketone markedly reduced the IL-17-, IL-1beta-, or TNF-alpha-induced IL-6 gene expression. Dithiocarbamate interleukin 1 beta Homo sapiens