Title : Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites.

Pub. Date : 2002 Jan 8

PMID : 11773615






1 Functional Relationships(s)
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1 Although the biological activities of MIF are presumed to require a receptor-based mechanism of action, the protein is also a tautomerase and has a catalytically active N-terminal proline that is invariant in structurally homologous bacterial isomerases. Proline macrophage migration inhibitory factor Homo sapiens