Pub. Date : 2002 Jan
PMID : 11772425
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ACAT is present in a variety of tissues and is responsible for catalyzing the conversion of free cholesterol to the more readily stored cholesteryl esters. | Cholesterol | carboxylesterase 1 | Homo sapiens |
| 2 | Partial ACAT inhibition with specific agents has resulted in lesion regression and decreased progression, whereas complete ACAT inhibition via genetic alterations has led to an exacerbation of cholesterol deposition in tissues in animal models. | Cholesterol | carboxylesterase 1 | Homo sapiens |