Pub. Date : 2001 Dec 14
PMID : 11755133
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Apomorphine, dopamine and phenylethylamine reduce the proportion of phosphorylated insulin receptor substrate 1. | Phenethylamines | insulin receptor substrate 1 | Homo sapiens |
| 2 | In a second set of experiments, we measured the ability of dopamine, apomorphine, phenylethylamine and pergolide to inhibit the phosphorylation (or increase the dephosphorylation) of the insulin receptor substrate (IRS)-1, a major intracellular substrate of the insulin-like growth factor (IGF)-1 receptor. | Phenethylamines | insulin receptor substrate 1 | Homo sapiens |
| 3 | Dopamine, apomorphine and phenylethylamine all reduced to zero the level of phosphorylated IRS-1 with potencies ranging between 0.01 and 1 microM. | Phenethylamines | insulin receptor substrate 1 | Homo sapiens |