Title : Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.

Pub. Date : 2001 Nov 22

PMID : 11753652






1 Functional Relationships(s)
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Protein Name
Organism
1 Abl was regulated efficiently when its SH3 domain was replaced with a heterologous SH3 from c-Src that binds a different spectrum of proline-rich ligands, but not by substitution of a modular WW domain with similar ligand-binding specificity. Proline SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens