Title : Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells.

Pub. Date : 2002 Jan

PMID : 11751282






1 Functional Relationships(s)
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1 We conclude that putative ligand-mediated activation of PPARgamma decreases LH- and/or insulin-driven theca cell androgen production by impairing the ability of CYP17 to synthesize androstenedione from available progestins. Androstenedione cytochrome P450 family 17 subfamily A member 1 Homo sapiens