Title : High levels of the MDM2 oncogene in paediatric rhabdomyosarcoma cell lines may confer multidrug resistance.

Pub. Date : 2001 Nov 30

PMID : 11742497






1 Functional Relationships(s)
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1 In 2 of the lines, SCMC and RD, the mdm2 gene caused between 2-fold and 61-fold increase in resistance to vincristine, etoposide and doxorubicin but not to cisplatin. Etoposide MDM2 proto-oncogene Homo sapiens