Pub. Date : 2002 Jan
PMID : 11731804
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 A resolution in the presence and absence of AdoDATO (S-adenosyl-1,8-diamino-3-thiooctane), a compound containing both substrate and product moieties. | S-adenosyl-3-thio-1,8-diaminooctane | spermidine synthase | Homo sapiens |
| 2 | The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 A resolution in the presence and absence of AdoDATO (S-adenosyl-1,8-diamino-3-thiooctane), a compound containing both substrate and product moieties. | S-adenosyl-3-thio-1,8-diaminooctane | spermidine synthase | Homo sapiens |
| 3 | The AdoDATO binding site is lined with residues conserved in PAPT enzymes from bacteria to humans, suggesting a universal catalytic mechanism. | S-adenosyl-3-thio-1,8-diaminooctane | spermidine synthase | Homo sapiens |