Title : Gene expression of monocyte chemoattractant protein-1 in human monocytes by exposure to advanced glycosylation end products.

Pub. Date : 2001 Jan

PMID : 11730565






4 Functional Relationships(s)
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1 RESULTS: AGEP-BSA stimulated monocytes to express MCP-1 mRNA in a glucose-concentration-related fashion. Glucose C-C motif chemokine ligand 2 Homo sapiens
2 The levels of MCP-1 mRNA were increased slightly when monocytes were exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 20 mmol/L), and increased markedly when exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 50 mmol/L), but decreased slightly when exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 80 mmol/L). Glucose C-C motif chemokine ligand 2 Homo sapiens
3 The levels of MCP-1 mRNA were increased slightly when monocytes were exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 20 mmol/L), and increased markedly when exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 50 mmol/L), but decreased slightly when exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 80 mmol/L). Glucose C-C motif chemokine ligand 2 Homo sapiens
4 The levels of MCP-1 mRNA were increased slightly when monocytes were exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 20 mmol/L), and increased markedly when exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 50 mmol/L), but decreased slightly when exposed to AGEP-BSA 200 mg/L (glycosylated with glucose 80 mmol/L). Glucose C-C motif chemokine ligand 2 Homo sapiens