Title : Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling.

Pub. Date : 2001 Dec 3

PMID : 11726515






1 Functional Relationships(s)
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Protein Name
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1 Tyr209 within the C-terminal SH3 domain of Grb2 was identified as one of the tyrosine phosphorylation sites, and phosphorylation of Tyr209 abolished the binding of the SH3 domain to a proline-rich Sos peptide in vitro. Proline growth factor receptor bound protein 2 Homo sapiens