Title : Conjugated polyhydroxybenzene derivatives block tumor necrosis factor-alpha-mediated nuclear factor-kappaB activation and cyclooxygenase-2 gene transcription by targeting IkappaB kinase activity.

Pub. Date : 2001 Dec

PMID : 11723253






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Both agents inhibited the TNF-alpha- or TPA-induced expression of cyclooxygenase (COX)-2 mRNA and protein, COX-2 promoter activity, and prostaglandin E2 (PGE2) production. Tetradecanoylphorbol Acetate mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Both agents inhibited the TNF-alpha- or TPA-induced expression of cyclooxygenase (COX)-2 mRNA and protein, COX-2 promoter activity, and prostaglandin E2 (PGE2) production. Tetradecanoylphorbol Acetate mitochondrially encoded cytochrome c oxidase II Homo sapiens