Title : A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin.

Pub. Date : 2001 Dec 4

PMID : 11717412






1 Functional Relationships(s)
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1 The rank order of potencies for this process (ibuprofen > celecoxib > valdecoxib > rofecoxib > etoricoxib) parallels that obtained for the inhibition of Cox-1-mediated thromboxane B(2) production by calcium ionophore-stimulated platelets. Etoricoxib mitochondrially encoded cytochrome c oxidase I Homo sapiens