Title : The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial.

Pub. Date : 2001 Nov 15

PMID : 11704395






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Eniporide specifically inhibits the NHE-1 isoform and has been shown to limit infarct size in experimental models. eniporide solute carrier family 9 member A1 Homo sapiens
2 CONCLUSIONS: In this large study administration of the NHE-1 inhibitor eniporide, before reperfusion therapy in patients with acute ST elevation MI, did not limit infarct size or improve clinical outcome. eniporide solute carrier family 9 member A1 Homo sapiens