Title : Nonsteroidal anti-inflammatory drugs suppress T-cell activation by inhibiting p38 MAPK induction.

Pub. Date : 2002 Jan 11

PMID : 11700329






1 Functional Relationships(s)
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1 Whereas the inhibition of nuclear factor-kappaB by aspirin and sodium salicylate can be partly accounted for by their binding to IkappaB kinase-beta, the broad range of transcriptional targets of NSAID suggests that the products of COX activity might affect one or more among the early steps in the TCR-signaling cascade. Sodium Salicylate inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens