Title : Transport activity and surface expression of the Na+-Ca2+ exchanger NCX1 are inhibited by the immunosuppressive agent cyclosporin A and by the nonimmunosuppressive agent PSC833.

Pub. Date : 2002 Jan 25

PMID : 11700317






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclosporin A (CsA) treatment of HEK 293 cells expressing the rat heart RHE-1 (NCX1.1, EMBL accession number ) or the rat brain RBE-2 (NCX1.5, GenBank(TM) accession number ) Na(+)-Ca(2+) exchanger inhibited their transport activity in a concentration-dependent manner. Cyclosporine solute carrier family 8 member A1 Rattus norvegicus