Pub. Date : 2001 Dec
PMID : 11698260
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line. | lysophosphatidic acid | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | LPA stimulated phosphorylation of Akt in a time-dependent manner in both intact and toxin-treated AML12 hepatocytes. | lysophosphatidic acid | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Wortmannin and LY-294002 abolished phosphorylation of Akt, further supporting activation of PI 3-kinase/Akt as a signaling pathway, which mediates hepatocyte protection by LPA. | lysophosphatidic acid | thymoma viral proto-oncogene 1 | Mus musculus |
| 4 | Wortmannin and LY-294002 abolished phosphorylation of Akt, further supporting activation of PI 3-kinase/Akt as a signaling pathway, which mediates hepatocyte protection by LPA. | lysophosphatidic acid | thymoma viral proto-oncogene 1 | Mus musculus |
| 5 | Cell protection by LPA involves activation of the mitogen-activated protein kinase Erk1/Erk2 cascade and PI 3-kinase-dependent phosphorylation of Akt. | lysophosphatidic acid | thymoma viral proto-oncogene 1 | Mus musculus |