Title : Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae.

Pub. Date : 2001 Nov

PMID : 11694577






1 Functional Relationships(s)
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1 The sphingolipid synthesis defect in lag1 Delta lac1 Delta cells can be partially corrected by overexpression of YPC1 or YDC1, encoding ceramidases that have been reported to have acyl-CoA-independent ceramide synthesis activity. Acyl Coenzyme A alkaline dihydroceramidase Saccharomyces cerevisiae S288C