Pub. Date : 2001 Dec
PMID : 11689682
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cyclic AMP (cAMP)-responsive factor CREB induces target gene expression via constitutive (Q2) and inducible (KID, for kinase-inducible domain) activation domains that function synergistically in response to cellular signals. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |
| 2 | The cyclic AMP (cAMP)-responsive factor CREB induces target gene expression via constitutive (Q2) and inducible (KID, for kinase-inducible domain) activation domains that function synergistically in response to cellular signals. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |
| 3 | Here we investigate the mechanism underlying cooperativity between the Q2 domain and KID in CREB by in vitro transcription assay with naked DNA and chromatin templates containing the cAMP-responsive somatostatin promoter. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |
| 4 | Correspondingly, overexpression of hTAFII130 potentiated CREB activity in cells exposed to cAMP, but had no effect on reporter gene expression in unstimulated cells. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |