Title : The effects of aprotinin and steroids on generation of cytokines during coronary artery surgery.

Pub. Date : 2001 Oct

PMID : 11688002






2 Functional Relationships(s)
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1 IL-8 levels in control patients were significantly higher compared with patients treated with aprotinin and patients treated with methylprednisolone 1 hour after CPB (p < 0.05). Methylprednisolone C-X-C motif chemokine ligand 8 Homo sapiens
2 CONCLUSION: This study showed that methylprednisolone suppresses TNF-alpha, IL-6, and IL-8 release; however, aprotinin attenuates IL-8 release alone. Methylprednisolone C-X-C motif chemokine ligand 8 Homo sapiens