Title : 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells.

Pub. Date : 2001 Dec 28

PMID : 11687581






1 Functional Relationships(s)
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1 Furthermore, pretreatment with wortmannin, an inhibitor of phosphatidylinositol 3 (PI3)-kinase, inhibited 15-d-PGJ2-induced ERK activation and c-fos mRNA expression, suggesting that PI3-kinase is involved in the process. Phosphatidylinositols mitogen-activated protein kinase 1 Homo sapiens