Title : Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer.

Pub. Date : 2001 Aug

PMID : 11685722






1 Functional Relationships(s)
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1 Docetaxel is believed to have a twofold mechanism of antineoplastic activity: (1) inhibition of microtubular depolymerization, and (2) attenuation of the effects of bcl-2 and bcl-xL gene expression. Docetaxel BCL2 like 1 Homo sapiens