Title : Evidence for the existence of a distinct SO(4)(--)-OH(-) exchange mechanism in the human proximal colonic apical membrane vesicles and its possible role in chloride transport.

Pub. Date : 2001 Nov

PMID : 11682697






1 Functional Relationships(s)
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1 Recent studies have demonstrated that mutations in human downregulated in adenoma gene (DRA) result in congenital chloride diarrhea (CLD), and that DRA may be involved in chloride transport across the intestinal apical domains. Chlorides solute carrier family 26 member 3 Homo sapiens