Title : Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15.

Pub. Date : 2001 Oct

PMID : 11676863






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 P-Glycoprotein, which mediates multidrug resistance (MDR) in cancer chemotherapy, is a principal target of cyclosporin A and [3"-keto-Bmt(1)]-[Val(2)]-cyclosporin (valspodar; PSC 833). valspodar ATP binding cassette subfamily B member 1 Homo sapiens