Title : High Catalytic Activity of Chiral Amino Alcohol Ligands Anchored to Polystyrene Resins.

Pub. Date : 1998 Sep 4

PMID : 11672264






1 Functional Relationships(s)
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1 The resulting epoxy-functionalized resins 4 have been submitted to completely regioselective (C-3 attack) and stereospecific ring-opening with secondary amines [piperidine (a), N-methylpiperazine (b), and cis-2,6-dimethylpiperidine (c)] in the presence of lithium perchlorate to afford (2R,3R)-3-(dialkylamino)-2-hydroxy-3-phenylpropoxy resin ethers 5a-c. Amines complement C3 Homo sapiens