Title : Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway.

Pub. Date : 2001 Oct 4

PMID : 11641785






1 Functional Relationships(s)
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1 Decreased expression of BRCA1 led to sensitivity to the DNA damaging agents cisplatin and etoposide, resistance to the microtubule-interfering agents (MIA) taxol and vincristine. Etoposide BRCA1 DNA repair associated Homo sapiens